Espinoza JL, Elbadry MI, Chonabayashi K, et al. Hematopoiesis by iPSC-derived hematopoietic stem cells of aplastic anemia that escape cytotoxic T-cell attack. Blood Adv. 2018;2(4):390-400

Autor:	Tatsuhiko Ozawa, Shinji Nakao, Tatsuya Imi, Hassan A. Hassanein, Yoshitaka Zaimoku, Takamasa Katagiri, Hiroyuki Maruyama, Kazuhisa Chonabayashi, Mahmoud I. Elbadry, Yoshiki Akatsuka, Hiroyuki Takamatsu, Yoshinori Yoshida, Amal Khalifa A. Noreldin, Koichi Akashi, Kenichi Harada, Noriharu Nakagawa, Katsuto Takenaka, J. Luis Espinoza, Hiroshi Hamana, Hiroyuki Kishi
Jazyk:	angličtina
Rok vydání:	2018
Předmět:	0301 basic medicine Immunobiology and Immunotherapy Genotype Induced Pluripotent Stem Cells CD8-Positive T-Lymphocytes Chimerism 03 medical and health sciences Mice 0302 clinical medicine medicine Cytotoxic T cell Animals Humans Aplastic anemia Cells Cultured business.industry Anemia Aplastic hemic and immune systems Hematology medicine.disease Hematopoietic Stem Cells Hematopoiesis Mice Inbred C57BL Haematopoiesis 030104 developmental biology Cancer research Stem cell Erratum business 030215 immunology T-Lymphocytes Cytotoxic
Popis:	Hematopoietic stem cells (HSCs) that lack HLA-class I alleles as a result of copy-number neutral loss of heterozygosity of the short arm of chromosome 6 (6pLOH) or HLA allelic mutations often constitute hematopoiesis in patients with acquired aplastic anemia (AA), but the precise mechanisms underlying clonal hematopoiesis induced by these HLA-lacking (HLA
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be92864256b6dd557a8da016a1c9efa1 https://europepmc.org/articles/PMC6134217/ Zobrazit plný text záznamu