Is reproduction costly? No increase of oxidative damage in breeding bank voles
Autor: | Paweł Koteja, Katarzyna M. Chrząścik, Łukasz Ołdakowski, Żaneta Piotrowska, Jan R. E. Taylor, Edyta T. Sadowska |
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Rok vydání: | 2012 |
Předmět: |
Male
Antioxidant Animal breeding Litter Size Physiology medicine.medical_treatment media_common.quotation_subject oxidative damage Aquatic Science Breeding medicine.disease_cause Protein oxidation Models Biological cost of reproduction Toxicology Lipid peroxidation Protein Carbonylation chemistry.chemical_compound Pregnancy medicine oxidative stress Animals Body Size bank vole Molecular Biology Ecology Evolution Behavior and Systematics media_common chemistry.chemical_classification Reactive oxygen species biology Estradiol Arvicolinae Reproduction Organ Size biology.organism_classification Bank vole Oxidative Stress chemistry Insect Science Animal Science and Zoology Female Energy Metabolism Oxidative stress |
Zdroj: | The Journal of experimental biology. 215(Pt 11) |
ISSN: | 1477-9145 |
Popis: | SUMMARY According to life-history theory, investment in reproduction is associated with costs, which should appear as decreased survival to the next reproduction or lower future reproductive success. It has been suggested that oxidative stress may be the proximate mechanism of these trade-offs. Despite numerous studies of the defense against reactive oxygen species (ROS) during reproduction, very little is known about the damage caused by ROS to the tissues of wild breeding animals. We measured oxidative damage to lipids and proteins in breeding bank vole (Myodes glareolus) females after rearing one and two litters, and in non-breeding females. We used bank voles from lines selected for high maximum aerobic metabolic rates (which also had high resting metabolic rates and food intake) and non-selected control lines. The oxidative damage was determined in heart, kidneys and skeletal muscles by measuring the concentration of thiobarbituric acid-reactive substances, as markers of lipid peroxidation, and carbonyl groups in proteins, as markers of protein oxidation. Surprisingly, we found that the oxidative damage to lipids in kidneys and muscles was actually lower in breeding than in non-breeding voles, and it did not differ between animals from the selected and control lines. Thus, contrary to our predictions, females that bred suffered lower levels of oxidative stress than those that did not reproduce. Elevated production of antioxidant enzymes and the protective role of sex hormones may explain the results. The results of the present study do not support the hypothesis that oxidative damage to tissues is the proximate mechanism of reproduction costs. |
Databáze: | OpenAIRE |
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