Does the Presence of Sucrose in Pediatric Antibiotics Influence the Enamel Mineral Loss and the Streptococcus mutans Counts in Dental Biofilm?

Autor: Kátia Regina Netto dos Santos, Daniela Novaes Soares, Viviane Santos da Silva Pierro, Lucianne Cople Maia, Natalia Lopes Pontes Iorio, Andréa Gonçalves Antonio
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Brazilian Dental Journal, Volume: 26, Issue: 3, Pages: 249-257, Published: JUN 2015
Brazilian Dental Journal v.26 n.3 2015
Brazilian Dental Journal
Fundação Odontológica de Ribeirão Preto (FUNORP)
instacron:FUNORP
Popis: The role of antibiotics containing sucrose on the formation of dental caries is still controversial. This study aimed to investigate the effect of two antibiotics (amoxicillin and potassium clavulanate suspension), with and without sucrose, on human dental hardness and Streptococcus mutans counts in dental biofilm. Primary tooth fragments (n=72) were coated with nail varnish leaving a window of 2.25 mm diameter. Specimens were fixed in 24-well polystyrene plates, containing BHI medium. S. mutans (clinical strains) represented the inoculum to form biofilm on the fragments for 24 h. Twelve fragments were separated for the initial count of microorganisms (baseline). The other fragments were divided into 4 groups (n=12) of treatment: G1 (Clavulin(r)), G2 (Betamox(r)), G3 (chlorhexidine 0.12%), G4 (sucrose 10%). All specimens had their self-control area (covered area). The cross-sectional microhardness (CSMH) was evaluated for each specimen. All the treated groups had a loss of hardness compared to their self-controls (p
Databáze: OpenAIRE