Does the Presence of Sucrose in Pediatric Antibiotics Influence the Enamel Mineral Loss and the Streptococcus mutans Counts in Dental Biofilm?
Autor: | Kátia Regina Netto dos Santos, Daniela Novaes Soares, Viviane Santos da Silva Pierro, Lucianne Cople Maia, Natalia Lopes Pontes Iorio, Andréa Gonçalves Antonio |
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Jazyk: | angličtina |
Rok vydání: | 2015 |
Předmět: |
Sucrose
medicine.drug_class Varnish Antibiotics Colony Count Microbial antibiotics Microbiology Streptococcus mutans chemistry.chemical_compound medicine Humans Child Dental Enamel General Dentistry Minerals biology Enamel paint Chemistry Chlorhexidine Biofilm Amoxicillin biology.organism_classification stomatognathic diseases visual_art Biofilms primary tooth visual_art.visual_art_medium dental biofilm microhardness medicine.drug |
Zdroj: | Brazilian Dental Journal, Volume: 26, Issue: 3, Pages: 249-257, Published: JUN 2015 Brazilian Dental Journal v.26 n.3 2015 Brazilian Dental Journal Fundação Odontológica de Ribeirão Preto (FUNORP) instacron:FUNORP |
Popis: | The role of antibiotics containing sucrose on the formation of dental caries is still controversial. This study aimed to investigate the effect of two antibiotics (amoxicillin and potassium clavulanate suspension), with and without sucrose, on human dental hardness and Streptococcus mutans counts in dental biofilm. Primary tooth fragments (n=72) were coated with nail varnish leaving a window of 2.25 mm diameter. Specimens were fixed in 24-well polystyrene plates, containing BHI medium. S. mutans (clinical strains) represented the inoculum to form biofilm on the fragments for 24 h. Twelve fragments were separated for the initial count of microorganisms (baseline). The other fragments were divided into 4 groups (n=12) of treatment: G1 (Clavulin(r)), G2 (Betamox(r)), G3 (chlorhexidine 0.12%), G4 (sucrose 10%). All specimens had their self-control area (covered area). The cross-sectional microhardness (CSMH) was evaluated for each specimen. All the treated groups had a loss of hardness compared to their self-controls (p |
Databáze: | OpenAIRE |
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