Cushing's Syndrome in Childhood: Postoperative Management

Autor: Grant Db, Williams Di, G. H. Newns, S Raiti
Rok vydání: 1972
Předmět:
Zdroj: Archives of Disease in Childhood. 47:597-601
ISSN: 1468-2044
0003-9888
DOI: 10.1136/adc.47.254.597
Popis: Of 8 children with Cushing9s syndrome, 7 had tumours and 1 bilateral adrenal hyperplasia. All had hypertension; 5 cases also showed virilization; only 3 had short stature. All excreted raised urinary 17KS and 17OHCS. Pyelography showed displaced kidneys on the affected side in 5 cases. Early postoperative complications occurred in 4 cases. 2 patients developed adrenal crisis. In 1 patient the blood pressure rose to very high levels but subsequently fell to normal. The fourth patient developed severe hypertension and acute pancreatitis and died. One patient died from pneumonia 3½ years after operation. A scheme for postoperative replacement therapy with cortisol is given.
Databáze: OpenAIRE