Supplementary Figure 3 from Bridging the Gap between Preclinical and Clinical Studies Using Pharmacokinetic–Pharmacodynamic Modeling: An Analysis of GDC-0973, a MEK Inhibitor

Autor: John Prescott, Marcia Belvin, Sanh Tan Lam, Ron Aoyama, Blake T. Aftab, Yongchang Shi, Klaus P. Hoeflich, Edna F. Choo, Geoffrey Del Rosario, Congfen Li, Peiwen Yu, Jean-Francois Martini, Lillian Lee, Joseph A. Ware, Amy Peterson, Laurent Vernillet, Harvey Wong
Rok vydání: 2023
DOI: 10.1158/1078-0432.22445543
Popis: PDF file, 66KB, Plot of observed versus predicted GDC-0973 plasma concentrations following fitting of PK model (Figure 1A) to mean GDC-0973 plasma concentration-time data from patients in cohort 1.
Databáze: OpenAIRE