Evaluation of tolerability and skin changes after application of topical antiaging products based on Sibanid SG®, plant stem cells and regenerative and biostimulating active ingredients
| Autor: | Maria Ferrillo, Marianna Donnarumma, Anna Perrotta, Mariateresa Cantelli, Gabriella Fabbrocini, Mirella D'Andrea |
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| Přispěvatelé: | D'Andrea, Mirella, Perrotta, Anna, Ferrillo, Maria, Cantelli, Mariateresa, Donnarumma, Marianna, Fabbrocini, Gabriella |
| Rok vydání: | 2019 |
| Předmět: |
Adult
Dermatology Pharmacology Administration Cutaneous Skin Aging 030207 dermatology & venereal diseases 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Dermis Hyaluronidase Plant Cells Hyaluronic acid Humans Regeneration Medicine Topical - Skin cream Skin Microscopy Confocal biology business.industry Stem Cells Elastase Middle Aged Elasticity Oxidative Stress medicine.anatomical_structure Tolerability chemistry Skin aging - Administration biology.protein Collagenase Female Dermatologic Agents Plant Preparations business Elastin medicine.drug |
| Zdroj: | Giornale Italiano di Dermatologia e Venereologia. 154 |
| ISSN: | 1827-1820 0392-0488 |
| DOI: | 10.23736/s0392-0488.18.06104-7 |
| Popis: | BACKGROUND The oxidative stress, the UV radiations, the matrix metalloproteinases (MMPs) and the hyaluronidase enzyme play an extremly important role in skin aging processes, leading an increasing production of elastase, collagenase and hyaluronidase that brings to degradation of collagen, elastin and hyaluronic acid respectively. They are responsible to provide strength, elasticity and moisture to the skin. Innovative devices were developed based on the effective ingredients against hyaluronidase and MMP. The inhibition of the destructuring enzymes of the dermis is the main mechanism of action of Bioliftan treatment, and this process is mainly addressed to hyaluronidase and MMP inhibition. The aim of our study was to evaluate the efficacy, tolerability and skin changes induced by antiaging topical based on Sibanid SG®, plant stem cells and regenerative and biostimulating active ingredients. The products tested are Bioliftan Day cream and Bioliftan concentrate. METHODS All parameters were evaluated before the beginning of treatment (T0), and 60 (T1) days later. The evaluation of the effectiveness of the products was performed by clinical examination, photographic and instrumental documentation by corneometry, X-rite, elastometry, Moisture Meter EpiD, Confocal microscopy. RESULTS The products tested after 60 days have induced an increase of hydration of the external cutaneous layers (P |
| Databáze: | OpenAIRE |
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