Non-functioning adrenocortical carcinoma
| Autor: | Pham Minh Thong, Tran Ngoc Minh, Bui-Van Giang, Nguyen Minh Duc, Le Tuan Linh, Thieu-Thi Tra My, Luong Viet Bang, Bui-Van Lenh |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Pathology Adrenal tumor Adrenocortical carcinoma Proliferative index R895-920 Case Report Malignancy 030218 nuclear medicine & medical imaging 03 medical and health sciences Medical physics. Medical radiology. Nuclear medicine 0302 clinical medicine medicine Adjuvant therapy Radiology Nuclear Medicine and imaging Mitotane Pathological Rare neoplasm business.industry food and beverages medicine.disease Histopathology business 030217 neurology & neurosurgery medicine.drug Calcification |
| Zdroj: | Radiology Case Reports, Vol 16, Iss 6, Pp 1329-1334 (2021) Radiology Case Reports |
| ISSN: | 1930-0433 |
| Popis: | Adrenocortical carcinoma (ACC) is a rare malignancy that arises from the adrenal cortex and can be classified as either non-functioning or functioning. A patient with non-functioning ACC may present no specific symptoms. Imaging analysis can provide some information to a clinician who suspects ACC, such as tumor size, density, washout, necrosis, hemorrhage, and calcification. Histopathology is used to confirm and determine the origin of the malignancy and can provide relevant prognostic information. Microscopic findings can be used to obtain information such as the Weiss score, resection surface features, Ki-67 proliferative index, and the degree of capsular and vascular invasion. Surgery can be curative for localized tumors, and adjuvant therapy using mitotane and cytotoxic chemotherapy is often employed for advanced-stage tumors. We describe a case report of a 32-year-old man with a non-functioning ACC that highlights the importance of radiological and pathological features in the diagnosis of ACC and their use as prognostic factors. |
| Databáze: | OpenAIRE |
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