Sevoflurane Alone and Propofol with or without Remifentanil for Electroconvulsive Therapy—a Randomised, Crossover Study
| Autor: | Mehmet Ozcan Ersoy, Hüseyin İlksen Toprak, Cemil Colak, G. Erdogan Kayhan, Taylan Şahin, Mahmut Durmuş, Zekine Begeç, H. Konur |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
Male Methyl Ethers Adolescent medicine.medical_treatment Remifentanil Critical Care and Intensive Care Medicine Sevoflurane Electroconvulsive therapy Piperidines medicine Humans In patient Prospective Studies Muscle paralysis Electroconvulsive Therapy Propofol Anesthetics Cross-Over Studies business.industry Middle Aged Crossover study Regimen Anesthesiology and Pain Medicine Anesthesia Female business medicine.drug |
| Zdroj: | Anaesthesia and Intensive Care. 41:202-206 |
| ISSN: | 1448-0271 0310-057X |
| DOI: | 10.1177/0310057x1304100209 |
| Popis: | We compared the effectiveness of three anaesthetic regimens (propofol alone, propofol with remifentanil and sevoflurane alone), with respect to seizure duration and seizure quality in patients undergoing electroconvulsive therapy. Thirty-nine patients underwent a total of 234 electroconvulsive therapy treatments in this prospective, observer blinded, crossover study. Each patient received either propofol 1 mg/kg alone (Group P), propofol 0.5 mg/kg and remifentanil 1 µg/kg (Group R), or sevoflurane alone 6% (Group S) for their initial electroconvulsive therapy session. The patients subsequently received an alternative regimen in their next session, such as from propofol 1 mg/kg alone to propofol 0.5 mg/kg and remifentanil 1 µg/kg, from propofol 0.5 mg/kg and remifentanil 1 µg/kg to sevoflurane alone 6%, or from sevoflurane alone 6% to a continuing alternation between drugs at each session, until their sixth session. Muscle paralysis was achieved with 1 mg/kg succinylcholine. Seizure duration, postictal suppression index, early and midictal amplitude were recorded. The mean motor and electroencephalogram seizure durations were significantly longer in Groups P and R compared to Group S (P |
| Databáze: | OpenAIRE |
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