Effects of Terbutaline Sulfate on Physiological and Biomechanical as Well as Perceived Exertion in Healthy Active Athletes: A Pilot Study
| Autor: | Hanen Hafedh, Ramzi Bettayeb, Bianca Miarka, Nicola Luigi Bragazzi, Maamer Slimani |
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| Rok vydání: | 2019 |
| Předmět: |
Physical Therapy
Sports Therapy and Rehabilitation doping 030204 cardiovascular system & hematology blood glucose concentration Placebo 03 medical and health sciences 0302 clinical medicine Physiology (medical) Heart rate heart rate Medicine Aerobic exercise lcsh:Sports medicine Rating of perceived exertion blood arterial pressures business.industry β2‐agonist VO2 max Terbutaline Sulfate 030229 sport sciences Section II - Exercise Physiology & Sports Medicine vVO2max Blood pressure Anesthesia lcsh:RC1200-1245 business human activities |
| Zdroj: | Journal of Human Kinetics Journal of Human Kinetics, Vol 69, Iss 1, Pp 169-178 (2019) |
| ISSN: | 1640-5544 |
| Popis: | This study aimed to investigate the effects of beta2‐agonist terbutaline sulfate (TER) at a supra‐therapeutic dose (8 mg) on aerobic exercise performance. Twelve (6 females and 6 males) amateur athletes familiarized with all experimental procedures had their anthropometric data obtained on day 1. On days 2 and 3 either 8 mg of TER or a placebo (PLA) was administered orally (double‐blind manner) to participants who had rested for 3 h prior to aerobic exercise performance 20 m multistage fitness test (MSFT)]. This test was used to predict maximal oxygen uptake (VO2max) and velocity at which VO2max occurs (vVO2max). The Borg rating of perceived exertion (RPE), cardiovascular variables [heart rate (HR) and blood pressure (BP)] and blood glucose concentration [BGC] were obtained 15 min pre‐ and immediately post‐MSFT. Significant mean group differences were reported between PLA and TER groups (p < 0.05), respectively, in the RPE (15.6 ± 1.2 vs. 17.3 ± 1.5 a.u.), maximum heart rate (HRmax: 191.2 ± 7.1 vs. 197.2 ± 8.6 bpm) and BGC (118.4 ± 18.3 vs. 141.2 ± 15.8 mg/dL) post‐MSFT. The main effect of gender (male vs. female) in TER and PLA groups (p< 0.05) was observed, with higher estimated VO2max, vVO2max, HRmax and a lower mean HR pre‐test in male than female athletes. For these reasons, the inclusion of TER in the Prohibited List should be re‐discussed because of the lack of ergogenic effects. |
| Databáze: | OpenAIRE |
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