HIV Incidence, Retention, and Changes of High-Risk Behaviors Among Rural Injection Drug Users in Guangxi, China
| Autor: | Liu Wei, Thomas Perdue, Rongjian Li, J. Brooks Jackson, Scott Rose, Shenghan Lai, Michelle Rodolph, Li Zhang, Ben Mâsse, Shizhu Liu, Jie Chen, Shaoping Wang, Yuhua Ruan, Geetha Beauchamp, Feng Zhou, Yiming Shao |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
Male Rural Population Health Knowledge Attitudes Practice medicine.medical_specialty Patient Dropouts Adolescent Medicine (miscellaneous) HIV Infections Heroin Cohort Studies HIV Seroprevalence Humans Medicine Needle Sharing Prospective Studies Substance Abuse Intravenous Prospective cohort study Needle sharing Unsafe Sex business.industry Incidence (epidemiology) virus diseases Middle Aged Retention rate medicine.disease Surgery Substance abuse Psychiatry and Mental health HIV-1 Female Observational study business Follow-Up Studies Demography Cohort study medicine.drug |
| Zdroj: | Substance Abuse. 27:53-61 |
| ISSN: | 1547-0164 0889-7077 |
| DOI: | 10.1300/j465v27n04_07 |
| Popis: | A prospective observational study of HIV seroincidence among high-risk injection drug users (IDU) was carried out in Guangxi, China. The primary objectives of this study were (1) to estimate HIV seroincidence (2) to estimate participant retention rate and (3) to evaluate changes in drug use and sexual behavior over a one year period.Five hundred HIV seronegative IDU were enrolled. HIV-1 incidence and retention rates were analyzed as a function of sociodemographic, behavioral, and recruitment variables. Changes in drug use and sexual behavior were analyzed at the baseline, 6-month and 12-month follow- up visits.At 12 months of follow-up, the HIV-1 incidence rate was 3.1 per 100 person years, [95% CI: (1.6%; 5.2%)] and participant retention rate was 87%. Reported changes in high-risk behaviors over 12-months included significant decreases in the frequency of heroin injection, in direct or indirect sharing of injection equipment, and in the number of sexual partners.HIV incidence is high among IDU in Guangxi, China despite a self-reported decrease in some high risk behaviors over the course of the study. |
| Databáze: | OpenAIRE |
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