Epidemiological and biochemical factors (serum ferritin and vitamin D) associated with premature hair graying in Egyptian population
| Autor: | Nermeen S.A. Abdel Fattah, Nawres taher Alrgig, Rania Mahmoud Elhusseiny |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Aging Population Physiology Dermatology vitamin D deficiency 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Statistical significance medicine Vitamin D and neurology Humans Family history Vitamin D education Hair Color education.field_of_study biology business.industry digestive oral and skin physiology medicine.disease Ferritin 030220 oncology & carcinogenesis Ferritins biology.protein Etiology Egypt business Body mass index |
| Zdroj: | Journal of cosmetic dermatologyREFERENCES. 20(6) |
| ISSN: | 1473-2165 |
| Popis: | The etiology of premature hair graying (PHG) remains incompletely understood with limited treatment options, although has profound impacts on patient's quality of life.To assess demographic and clinical profiles of Egyptian PHG patients and explore association of various epidemiological risk factors and serum vitamin D and ferritin levels with PHG.Three hundred PHG patients and equal number of controls, aged30 years, were included. Assessment of epidemiological and clinical characteristics, biometric data and stress perception using perceived stress scale (PSS-10) was done, with measurement of serum vitamin D and ferritin levels for all subjects. PHG was graded into mild, moderate, and severe if10, 10-100, and100 gray hairs, respectively. Statistical significance for various compared parameters was done employing suitable tests, with P-value ≤ .05 considered significant.Results reported significant positive relation of PHG with family history, sedentary life style, and stress (P = .001, .029, and .001, respectively), while no significant relation with smoking, body mass index, or frequent hair dyes use (3 per year) (P = .425, .5, and .65, respectively). No significant difference was found in mean vitamin D between patients and controls (23.79 ± 13.01 ng/mL vs 24.85 ± 13.19 ng/mL, P = .701), while low serum ferritin (20 ng/mL) was significantly associated with PHG (14.7 % patients vs 2.7% controls, P = .017).PHG in Egyptian population is significantly associated with positive family history, stress, sedentary life style, and low serum ferritin level, while role of vitamin D deficiency should be further evaluated. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|