Effect of duration from lingual nerve injury to undergoing microneurosurgery on improving sensory and taste functions: retrospective study
| Autor: | Kensuke Tanioka, Takashi Nakanishi, Itaru Tojyo, Shigeyuki Fujita, Yuta Yamamoto, Yukari Shintani |
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| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Taste lcsh:Surgery Sensory system 03 medical and health sciences 0302 clinical medicine medicine Lingual nerve Traumatic neuroma business.industry Research Retrospective cohort study lcsh:RD1-811 030206 dentistry Duration time to surgery medicine.disease Discrimination testing lcsh:RK1-715 Plastic surgery lcsh:Dentistry 030220 oncology & carcinogenesis Anesthesia Oral and maxillofacial surgery Peripheral nerve recovery Microneurosurgery business Schwann cells taste function |
| Zdroj: | Maxillofacial Plastic and Reconstructive Surgery Maxillofacial Plastic and Reconstructive Surgery, Vol 41, Iss 1, Pp 1-8 (2019) |
| ISSN: | 2288-8101 |
| Popis: | Background The prognosis of recovery following microneurosurgery for injured lingual nerves varies among individual cases. This study aimed to investigate if recovery ratios of sensory and taste functions are improved by the microneurosurgery within 6 months after lingual nerve injury. Methods We retrospectively assessed 70 patients who underwent microneurosurgery at the Wakayama Medical University Hospital for lingual nerve injuries between July 2004 and December 2016. Sensory and taste functions in lingual nerves were preoperatively evaluated using a static two-point discrimination test, an intact superficial pain/tactile sensation test, and a taste discrimination test. They were evaluated again at 12 and at 24 months postoperatively. The abundance ratio of Schwann cells in the excised traumatic neuromas was analyzed with ImageJ software following immunohistochemistry with anti S-100β antibody. Results In early cases (microneurosurgery within 6 months after the injury), recovery ratios of sensory and taste functions were not significantly different at 24 months after microneurosurgery compared with later cases (microneurosurgery more than 6 months after the injury). Meanwhile, the ratio of patients with taste recovery within 12 months after microneurosurgery was significantly decreased in late cases compared with early cases. The abundance ratio of Schwann cells in traumatic neuroma was also significantly lower in later cases. Conclusion Microneurosurgery more than 6 months after lingual nerve injury did not lead to decreased recovery ratio of sensory and taste functions, but it did lead to prolonged recovery of taste. This delay may be associated with a decrease in the abundance ratio of Schwann cells in traumatic neuromas. |
| Databáze: | OpenAIRE |
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