Acute Epiglottitis in the Immunocompromised Host: Case Report and Review of the Literature
| Autor: | Georg Aue, Mukil Natarajan, Cheng Chen, David Bianchi, John H. Powers |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Pediatrics
medicine.medical_specialty aplastic anemia medicine.medical_treatment Review Article Neutropenia Malignancy 03 medical and health sciences 0302 clinical medicine Throat Enterobacter cloacae medicine Intubation neutropenia Aplastic anemia 030223 otorhinolaryngology epiglottitis Epiglottitis business.industry medicine.disease Vaccination Infectious Diseases medicine.anatomical_structure Oncology 030220 oncology & carcinogenesis Absolute neutrophil count immunocompromise business malignancy |
| Zdroj: | Open Forum Infectious Diseases |
| ISSN: | 2328-8957 |
| Popis: | We present a case of acute epiglottitis in a 16-year-old with severe aplastic anemia. He was admitted with a history suggestive of a severe upper airway infection and an absolute neutrophil count of 0 per cubic millimeter. Despite his immunocompromised state, he presented with the classical signs and symptoms of epiglottitis. We review here the presentation and comorbidities of immunocompromised patients with epiglottitis. In addition, the appropriate choice of empirical antibiotic therapy is important for the management of epiglottitis in immunocompromised patients, especially in the post–Haemophilus influenza type B vaccination era. In our patient, Enterobacter cloacae was isolated from endoscopically directed throat cultures, and treatment was successful without the need for intubation. The current literature suggests that in immunocompromised patients, particularly those who are neutropenic, there is a potentially wide range of organisms, both bacterial and fungal, that may play a role in the pathology of acute epiglottitis. |
| Databáze: | OpenAIRE |
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