Gender-specific contribution of cardiometabolic index and lipid accumulation product to left ventricular geometry change in general population of rural China
Autor: | Zhao Li, Haoyu Wang, Yichen Tian, Lijun Zhang, Ning Ye, Shuang Chen, Xiaofan Guo, Yingxian Sun |
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Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
Male
lcsh:Diseases of the circulatory (Cardiovascular) system Left ventricular geometry Epidemiology Cardiometabolic index Rural Health 030204 cardiovascular system & hematology Concentric Ventricular Function Left 0302 clinical medicine Risk Factors Prevalence Eccentric 030212 general & internal medicine Adiposity education.field_of_study Ventricular Remodeling Gender-specific Middle Aged Lipids Quartile Echocardiography Cardiology Female Hypertrophy Left Ventricular Cardiology and Cardiovascular Medicine Research Article Adult medicine.medical_specialty China Population Adipose tissue 03 medical and health sciences Sex Factors Internal medicine Diabetes mellitus medicine Humans Obesity education Angiology Aged Dyslipidemias business.industry Waist-Hip Ratio Left ventricular remodeling Odds ratio medicine.disease Cross-Sectional Studies lcsh:RC666-701 Lipid accumulation product business Biomarkers |
Zdroj: | BMC Cardiovascular Disorders BMC Cardiovascular Disorders, Vol 18, Iss 1, Pp 1-11 (2018) |
ISSN: | 1471-2261 |
Popis: | Background Despite current interest in the unfavorable impact of cardiometabolic index (CMI) and lipid accumulation product (LAP) on diabetes and cardiovascular risk, information regarding the relation of CMI and LAP to left ventricular (LV) geometry has not been specifically addressed. We aimed to examine the hypothesis: (1) CMI and LAP represent an independent determinant of LV remodeling in general population of rural China; (2) there are gender differences in obesity-related alterations in terms of LV morphology. Methods The sample for this cross-sectional analysis included 11,258 participants (mean age 53.9 years; 54.0% females) who underwent assessment of basic metabolic and anthropometric parameters in rural areas of northeast China. Comprehensive echocardiography-defined LV geometric pattern was determined according to left ventricular mass index and relative wall thickness. Results The prevalence rate of eccentric and concentric LV hypertrophy (LVH) presented a proportional increase with elevated quartiles of CMI and LAP in a dose-response manner (all P |
Databáze: | OpenAIRE |
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