Gender-specific contribution of cardiometabolic index and lipid accumulation product to left ventricular geometry change in general population of rural China

Autor: Zhao Li, Haoyu Wang, Yichen Tian, Lijun Zhang, Ning Ye, Shuang Chen, Xiaofan Guo, Yingxian Sun
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Male
lcsh:Diseases of the circulatory (Cardiovascular) system
Left ventricular geometry
Epidemiology
Cardiometabolic index
Rural Health
030204 cardiovascular system & hematology
Concentric
Ventricular Function
Left
0302 clinical medicine
Risk Factors
Prevalence
Eccentric
030212 general & internal medicine
Adiposity
education.field_of_study
Ventricular Remodeling
Gender-specific
Middle Aged
Lipids
Quartile
Echocardiography
Cardiology
Female
Hypertrophy
Left Ventricular
Cardiology and Cardiovascular Medicine
Research Article
Adult
medicine.medical_specialty
China
Population
Adipose tissue
03 medical and health sciences
Sex Factors
Internal medicine
Diabetes mellitus
medicine
Humans
Obesity
education
Angiology
Aged
Dyslipidemias
business.industry
Waist-Hip Ratio
Left ventricular remodeling
Odds ratio
medicine.disease
Cross-Sectional Studies
lcsh:RC666-701
Lipid accumulation product
business
Biomarkers
Zdroj: BMC Cardiovascular Disorders
BMC Cardiovascular Disorders, Vol 18, Iss 1, Pp 1-11 (2018)
ISSN: 1471-2261
Popis: Background Despite current interest in the unfavorable impact of cardiometabolic index (CMI) and lipid accumulation product (LAP) on diabetes and cardiovascular risk, information regarding the relation of CMI and LAP to left ventricular (LV) geometry has not been specifically addressed. We aimed to examine the hypothesis: (1) CMI and LAP represent an independent determinant of LV remodeling in general population of rural China; (2) there are gender differences in obesity-related alterations in terms of LV morphology. Methods The sample for this cross-sectional analysis included 11,258 participants (mean age 53.9 years; 54.0% females) who underwent assessment of basic metabolic and anthropometric parameters in rural areas of northeast China. Comprehensive echocardiography-defined LV geometric pattern was determined according to left ventricular mass index and relative wall thickness. Results The prevalence rate of eccentric and concentric LV hypertrophy (LVH) presented a proportional increase with elevated quartiles of CMI and LAP in a dose-response manner (all P
Databáze: OpenAIRE
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