The noradrenergic innervation of the ovary in old rats
| Autor: | Elena Bronzetti, Carlo Cavallotti, Francesco Amenta, Fabio Ferrante, Alberto Ricci |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
medicine.medical_specialty
Aging Histocytochemistry Ovary Rats Inbred Strains Electrochemical detection Biology High-performance liquid chromatography Nervous System Fluorescence Rats Norepinephrine Endocrinology medicine.anatomical_structure Nerve Fibers Ageing Internal medicine medicine Catecholamine Animals Female Developmental Biology medicine.drug |
| Zdroj: | Mechanisms of ageing and development. 54(1) |
| ISSN: | 0047-6374 |
| Popis: | The influence of ageing on the noradrenergic innervation of the ovary was studied in female Wistar rats using high pressure liquid chromatography (HPLC) with electrochemical detection and catecholamine histofluorescence techniques. Old age was accompanied by a significant decrease in ovarian noradrenaline levels. In young animals (3-month-old) noradrenergic nerve fibres were distributed primarily to blood vessels and in lesser amounts to the interstitial glands. In aged animals (24-month-old) perivascular noradrenergic fibres were reduced by more than 40%; interstitial gland nerve fibres were reduced by approximately 20%. The possibility that impaired noradrenergic ovarian innervation occurring in old age may be in some way related with age-dependent failure in reproductive activity is discussed. |
| Databáze: | OpenAIRE |
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