Gaucher disease: assessment of skeletal involvement and therapeutic responses to enzyme replacement
Autor: | Ibrahim Fikry Abdelwahab, G. M. Pastores, A. M. Lorberboym, George D. Hermann |
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Rok vydání: | 1997 |
Předmět: |
Adult
Male Pathology medicine.medical_specialty Adolescent medicine.medical_treatment Splenectomy Scintigraphy Bone and Bones Central nervous system disease Bone Marrow medicine Humans Radiology Nuclear Medicine and imaging Child Radionuclide Imaging Pathological Gaucher Disease medicine.diagnostic_test business.industry Magnetic resonance imaging Enzyme replacement therapy medicine.disease Magnetic Resonance Imaging Recombinant Proteins Glucosylceramidase medicine.anatomical_structure Female Bone marrow Bone Diseases Tomography X-Ray Computed business |
Zdroj: | Skeletal Radiology. 26:687-696 |
ISSN: | 1432-2161 0364-2348 |
DOI: | 10.1007/s002560050313 |
Popis: | The clinical, pathological and radiological manifestations of type 1 Gaucher disease and the role of imaging techniques such as CT, MRI and sulfur-colloid scintigraphy in the management of these patients is discussed. MRI appears to be the most valuable imaging technique for evaluating bone marrow involvement and detecting disease activity. MRI is also useful in assessing therapeutic responses to enzyme replacement therapy. |
Databáze: | OpenAIRE |
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