Sensitivity of proliferating human breast epithelial cells to hypotonic treatment
| Autor: | Roscoe Stanyon, Stephen E. Goldstone, Sam Lan |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
Pathology
medicine.medical_specialty Cell Survival Cell growth Breast Neoplasms General Medicine Biology Epithelium Carcinoma Intraductal Noninfiltrating medicine.anatomical_structure Feeder Layer Hypotonic Solutions Oncology Cytology medicine Cancer research Humans Tonicity Female Surgery Radiosensitivity Fibroblast Human breast Cells Cultured |
| Zdroj: | Journal of Surgical Oncology. 21:258-260 |
| ISSN: | 1096-9098 0022-4790 |
| DOI: | 10.1002/jso.2930210413 |
| Popis: | An assay for colony-forming cells of breast epithelia derived from normal and malignant surgical specimens is described using an IMR 90 fibroblast feeder layer. Their radiosensitivity (DO: 120-172) is consistent with the proliferative origin of the colonies. Distilled water inhibits proliferation of a proportion of the colony-forming cells after a 1-minute exposure. Continued detection of colonies after 10 minutes of exposure indicates that it is an inefficient way of completely eradicating proliferating epithelial cells of normal and malignant origin. |
| Databáze: | OpenAIRE |
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