| Autor: |
Zude Chen, Riwei Yang, Yulong Xu, Leqi Liang, Shan Ao, Zuomin Wang, Ping Bai, Di Gu, Xiaolu Duan, Yongda Liu, Wen Zhong, Peng Xu, Tuo Deng, Guohua Zeng, Changning Wang |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Molecular pharmaceutics. 19(7) |
| ISSN: |
1543-8392 |
| Popis: |
Alcoholic liver disease (ALD) has a significant impact on human health and is one of the leading causes of liver disease mortality. The early and exact diagnosis of ALD is very important since the early stage of disease progression can be reversible. Although ALD can be evaluated by ultrasound, CT, or MRI, there is still no imaging technique sufficient in the diagnosis of early-stage ALD. Of the current studies, epigenetic modulation plays a significant role in the development and progression of ALD. In this work, we evaluate whether BRDs play a vital role in the early-stage ALD using our new PET imaging probe of BET proteins, [ |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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