Prognostic factors and effects of early surgical drainage in patients with peritonsillar abscess
| Autor: | Tomoyasu Tachibana, Michihiro Nakada, Yuya Ogawara, Yuko Matsuyama, Iku Abe-Fujisawa, Aiko Shimizu, Yasuharu Sato, Yorihisa Orita, Kazunori Nishizaki |
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| Rok vydání: | 2014 |
| Předmět: |
Microbiology (medical)
Adult Male medicine.medical_specialty Multivariate analysis Time Factors medicine.medical_treatment Tonsillitis Incision and drainage Medicine Humans Pharmacology (medical) Peritonsillar Abscess Abscess Retrospective Studies Univariate analysis Analysis of Variance biology business.industry Medical record C-reactive protein Age Factors medicine.disease Prognosis Surgery Infectious Diseases C-Reactive Protein biology.protein Drainage Female business |
| Zdroj: | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 20(11) |
| ISSN: | 1437-7780 |
| Popis: | Peritonsillar abscess is a frequently encountered otorhinolaryngological emergency, but the characteristics of patients with this disease have not been described in detail. The objective of this study was to delineate prognostic factors associated with peritonsillar abscess and the effects of early surgical drainage for the treatment of peritonsillar abscess. We conducted a retrospective analysis of the medical records of 240 consecutive patients with PTA during the period from 2007 to 2013. Univariate analysis indicated that the period between symptom onset and relief was significantly longer in patients with high levels of C-reactive protein (CRP) (>8.53 mg/dL, p = 0.0073) and without early surgical drainage of pus (p < 0.0001). Multivariate analysis identified both of these values as independently associated with longer duration of symptoms (high CRP, P < 0.0001; no early drainage, P < 0.0001). Univariate analysis indicated that the duration between symptom onset and complete recovery from the disease was significantly longer with age ≥40 years (P = 0.0004), no history of recurrent tonsillitis (P = 0.022), high CRP level (P = 0.0017), and no early surgical drainage of the abscess (P = 0.0014). Multivariate analysis identified older age (P = 0.0004), high CRP level (P = 0.0001), and no early drainage (P < 0.0001) as independently associated with longer duration between symptom onset and complete recovery. Early surgical drainage of the abscess is important for the treatment of peritonsillar abscess. Patients ≥40 years old with peritonsillar abscess and high CRP levels should be recognized as a high-risk group. |
| Databáze: | OpenAIRE |
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