A Multicenter Controlled Study to Evaluate Multiple Treatments With Nonthermal Focused Ultrasound for Noninvasive Fat Reduction
| Autor: | Dean Ad-El, Jeffrey M. Kenkel, Ruthie Amir, William Coleman, Robert Weiss, William P. Coleman |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Erythema Adolescent Abdominal Fat Pain Dermatology Cosmetic Techniques 030230 surgery Focused ultrasound law.invention 030207 dermatology & venereal diseases 03 medical and health sciences Young Adult 0302 clinical medicine Patient satisfaction Randomized controlled trial law medicine Humans Young adult Adverse effect Aged business.industry General Medicine Middle Aged Circumference Surgery Treatment Outcome Tolerability Patient Satisfaction High-Intensity Focused Ultrasound Ablation Female medicine.symptom Waist Circumference business |
| Zdroj: | Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]. 43(1) |
| ISSN: | 1524-4725 |
| Popis: | Background Demand for nonsurgical esthetic body procedures has led to the development of noninvasive techniques for reducing localized subcutaneous adipose tissue. Objective This study assessed multiple treatments with nonthermal focused ultrasound for noninvasive abdominal treatment of excess fat deposits. Materials and methods Subjects were randomly assigned to Group 1 for a 4-week control phase before undergoing 3 abdominal fat reduction treatments, at 2-week intervals, or to Group 2 for immediate treatment. Weight, abdominal circumference, tolerability to treatment, subject satisfaction, and adverse events were recorded. Results Weight remained stable in the 126 participants. Mean reduction in midline circumference was 2.5 ± 2.1 cm in the Group 1 and 3.5 ± 2.7 cm in the Group 2 at Week 22. The effect of multiple treatments was cumulative with a steady decrease in abdominal circumferences during the study. Erythema was observed in 28% of treatments but was mild and transient in nature. Subjects tolerated the treatments well and were satisfied with treatment outcome. Conclusion The study demonstrated the efficacy and safety of multiple nonthermal focused ultrasound treatments of excess abdominal fat deposits. Although the remodeling effect is minor compared with traditional surgical procedures, successive focused ultrasound treatments significantly reduced treatment area circumference, while avoiding invasive techniques and their associated disadvantages. |
| Databáze: | OpenAIRE |
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