Early-stage glottic carcinomas: effect of tumor location and full-length involvement on local tumor recurrence after radiation therapy
| Autor: | D S Shimm |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Glottis
medicine.medical_specialty Cord Epithelioma business.industry medicine.medical_treatment Anterior commissure medicine.disease Surgery Radiation therapy medicine.anatomical_structure medicine Carcinoma Humans Radiology Nuclear Medicine and imaging Radiology Neoplasm Recurrence Local Stage (cooking) business Complication Laryngeal Neoplasms |
| Zdroj: | Radiology. 192:873-875 |
| ISSN: | 1527-1315 0033-8419 |
| Popis: | PURPOSE: To correlate tumor location along the vocal cord with local control in stage I and II glottic carcinoma. MATERIALS AND METHODS: Sixty-five patients with stage I and 18 patients with stage II glottic cancer were irradiated with 4-MV x rays. Most patients received a total of 64-66 Gy, at a dose of 1.8-2.0 Gy/d. RESULTS: In stage I tumors, local-control probability was 96% +/- 2 (standard deviation); in stage II tumors, 67% +/- 15. When stages I and II were considered together, tumors that involved the full length of the vocal cord were more likely to recur (P = .069). In stage I tumors, treatment with < 2.0 Gy/d was statistically significantly (P = .038) associated with local recurrence. CONCLUSION: Poor outcome after irradiation could not be predicted with involvement of either the anterior commissure or posterior third of the vocal cord. Risk of tumor recurrence increased with full-length involvement, and in stage I tumors, with a daily fraction < 2.0 Gy. |
| Databáze: | OpenAIRE |
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