MICRODOSIMETRY AT NANOMETRIC SCALE WITH AN AVALANCHE-CONFINEMENT TEPC: RESPONSE AGAINST A HELIUM ION BEAM
Autor: | V. Conte, Andrea Pola, A.G. Amico, D. Mazzucconi, D. Bortot, Giada Petringa, G.A.P. Cirrone, P. Colautti, Alberto Fazzi, Stefano Pasquato, Stefano Agosteo |
---|---|
Rok vydání: | 2018 |
Předmět: |
Computer Simulation
Equipment Design Helium Models Theoretical Radiometry Nanotechnology Materials science Ion beam Proportional counter chemistry.chemical_element Bragg peak Secondary electrons 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Theoretical Models Radiology Nuclear Medicine and imaging Particle beam Range (particle radiation) Radiation Radiological and Ultrasound Technology Public Health Environmental and Occupational Health General Medicine Computational physics chemistry 030220 oncology & carcinogenesis Particle |
Zdroj: | Radiation protection dosimetry. 183(1-2) |
ISSN: | 1742-3406 |
Popis: | The tissue-equivalent proportional counter (TEPC) is the most accurate device for measuring the microdosimetric properties of a particle beam but, since the lower operation limit of common TEPCs is ~0.3 μm, no detailed information on the track structure of the impinging particles can be obtained. The pattern of particle interactions at the nanometric level is measured directly by only three different nanodosimeters worldwide: practical instruments are not yet available. In order to partially fill the gap between microdosimetry and track-nanodosimetry, a low-pressure avalanche-confinement TEPC was designed and constructed for simulating tissue-equivalent sites down to the nanometric region. The present paper aims at describing the response of this TEPC in the range 0.3 μm-25 nm to a 62 MeV/n 4He ion beam. The experimental results, for depths near the Bragg peak, show good agreement with FLUKA simulations and suggest that, for smaller depths, the distribution is highly influenced by secondary electrons. |
Databáze: | OpenAIRE |
Externí odkaz: |