Altered cardiac autonomic function after recovery from COVID‐19
Autor: | Ertuğrul Kurtoğlu, Erdal Aktürk, Ergün Kutlusoy, İbrahim Aktaş, Abdulmecit Afsin, Özlem Çağaşar |
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Přispěvatelé: | Kurtoğlu, Ertuğrul, Aktaş, İbrahim, Kutlusoy, Ergün |
Rok vydání: | 2021 |
Předmět: |
Autonomic function
medicine.medical_specialty Coronavirus disease 2019 (COVID-19) Autonomic Nervous System Electrocardiography Holter/event recorders Heart Rate Physiology (medical) Internal medicine medicine Diseases of the circulatory (Cardiovascular) system Humans Heart rate variability Balance (ability) SARS-CoV-2 business.industry heart rate variability Healthy subjects COVID-19 Heart Original Articles General Medicine Autonomic nervous system Nonlinear parameters RC666-701 Cardiology Population study Original Article Cardiology and Cardiovascular Medicine business circulatory and respiratory physiology |
Zdroj: | Annals of Noninvasive Electrocardiology Annals of Noninvasive Electrocardiology, Vol 27, Iss 1, Pp n/a-n/a (2022) |
ISSN: | 1542-474X 1082-720X |
DOI: | 10.1111/anec.12916 |
Popis: | Background Autonomic dysfunction may occur during the acute phase of COVID‐19. Heart rate variability (HRV) is a useful tool for the assessment of cardiac sympathetic and parasympathetic balance. We aimed to evaluate cardiac autonomic function by using HRV in subjects after recovery from COVID‐19 who had previously symptomatic and were followed outpatiently. Methods The study group composed of 50 subjects with a confirmed history of COVID‐19 and the control group composed of 50 healthy subjects without a history of COVID‐19 and vaccination. All the study participants underwent 2‐dimensional, pulsed‐ and tissue‐Doppler echocardiographic examinations and 24‐hour Holter monitoring for HRV analysis. Results Time domain parameters of SDNN, SDANN, SDNNi, RMSSD, pNN50, and HRV triangular index were all decreased in the study group when compared with the control group. Frequency domain parameters of TP, VLF, LF, HF, and HFnu were also decreased in the study group in comparison with the control group. LFnu was similar between groups. Nonlinear parameters of HRV including α1 and α2 decreased in the study group. By contrast, Lmax, Lmean, DET, REC, and Shannon entropy increased in the study population. Approximate and sample entropies also enhanced in the study group. Conclusions The present study showed that all three domain HRV significantly altered in patients after recovery from COVID‐19 indicating some degree of dysfunction in cardiac autonomic nervous system. HRV may be a useful tool for the detection of preclinical autonomic dysfunction in this group of patients. |
Databáze: | OpenAIRE |
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