MRI-guided cardiac-induced target motion tracking for atrial fibrillation cardiac radioablation
| Autor: | Giuseppe Sasso, Paul J. Keall, Beau Pontre, Suzanne Lydiard, Boris S. Lowe, Nicholas Hindley |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Cardiac arrhythmias
0299 Other Physical Sciences Population Tracking (particle physics) Motion Match moving Atrial Fibrillation medicine Humans Radiology Nuclear Medicine and imaging Non-invasive MRI-Linac education education.field_of_study Stereotactic radiotherapy medicine.diagnostic_test Cardiac cycle business.industry Radioablation Heart Magnetic resonance imaging Atrial fibrillation Hematology medicine.disease Magnetic Resonance Imaging Treatment efficacy Oncology Nuclear medicine business Mri guided |
| Zdroj: | Radiotherapy & Oncology |
| ISSN: | 0167-8140 |
| DOI: | 10.1016/j.radonc.2021.09.025 |
| Popis: | Background and purpose: Atrial fibrillation (AF) cardiac radioablation (CR) challenges radiotherapy tracking: multiple small targets close to organs-at-risk undergo rapid differential cardiac contraction and respiratory motion. MR-guidance offers a real-time target tracking solution. This work develops and investigates MRI-guided tracking of AF CR targets with cardiac-induced motion. Materials and methods: A direct tracking method (Trackingdirect) and two indirect tracking methods leveraging population-based surrogacy relationships with the left atria (Trackingindirect_LA) or other target (Trackingindirect_target) were developed. Tracking performance was evaluated using transverse ECG-gated breathhold MRI images from 15 healthy and 10 AF participants. Geometric and volumetric tracking errors were calculated, defined as the difference between the ground-truth and tracked target centroids and volumes respectively. Transverse, breath-hold, noncardiac-gated cine images were acquired at 4 Hz in 5 healthy and 5 AF participants to qualitatively characterize tracking performance on images more comparable to MRILinac acquisitions. Results: The average 3D geometric tracking errors for Trackingdirect, Trackingindirect_LA and Trackingindirect_target respectively were 1.7 ± 1.2 mm, 1.6 ± 1.1 mm and 1.9 ± 1.3 mm in healthy participants and 1.7 ± 1.3 mm, 1.5 ± 1.0 mm and 1.7 ± 1.2 mm in AF participants. For Trackingdirect, 88% of analyzed images had 3D geometric tracking errors |
| Databáze: | OpenAIRE |
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