Electrocardiographically indicated cardiovascular disease in sleep-disordered breathing

Autor: Terry Young, Laurel Finn, Paul E. Peppard, Khin Mae Hla, David J. Ende, Timothy J. Kinsey
Rok vydání: 2007
Předmět:
Zdroj: Sleepbreathing = SchlafAtmung. 12(3)
ISSN: 1520-9512
Popis: The evidence for a role of sleep-disordered breathing (SDB) in cardiovascular disease (CVD) is inconclusive and limited to clinic-based studies or population-based studies using historical CVD data. The authors investigated cross-sectional association of SDB, assessed by overnight polysomnography and described by frequency of apnea/hypopnea episodes (Apnea–Hypopnea Index, AHI), with screen-detected CVD consisting of cardiologist-confirmed, electrocardiographically indicated coronary artery disease (ECG-CAD), left ventricular hypertrophy (ECG-LVH), arrhythmias, and conduction abnormalities in a general population. Using multiple logistic regression with adjustments for covariables, there was no significant association of AHI with ECG-CAD, ECG-LVH by voltage, arrhythmias, or conduction abnormalities. There was, however, an association between AHI and ECG-LVH by Cornell criteria. Using AHI as categorical variable, the adjusted odds of ECG-CAD in AHI ≥ 5 vs
Databáze: OpenAIRE