Acceptability of Interventions to Reduce Mother-to-Child Transmission of HIV-1 in West Africa

Autor: François Dabis, M Cartoux, Coulibaly D, Laurent Mandelbrot, Van de Perre P, Blibolo D, Philippe Msellati, Rouamba O, Nicolas Meda
Rok vydání: 1996
Předmět:
Adult
Program evaluation
medicine.medical_specialty
ZIDOVUDINE
Immunology
Population
Psychological intervention
Developing country
HIV Infections
Pilot Projects
TRAITEMENT MEDICAL
DIAGNOSTIC
Acquired immunodeficiency syndrome (AIDS)
Pregnancy
GROSSESSE
Informed consent
Surveys and Questionnaires
Virology
Burkina Faso
medicine
Humans
Immunology and Allergy
PSYCHOLOGIE
Pregnancy Complications
Infectious
FOETUS
EFFICACITE
education
Randomized Controlled Trials as Topic
education.field_of_study
Maternal Transmission
Traditional medicine
SIDA
business.industry
AIDS Serodiagnosis
PROTECTION MATERNELLE ET INFANTILE
VIRUS HIV-1
PREVENTION SANITAIRE
medicine.disease
Infectious Disease Transmission
Vertical
Clinical trial
Cote d'Ivoire
FEMME
Family medicine
ENQUETE
Female
business
Attitude to Health
TRANSMISSION FOETOMATERNELLE
COMPORTEMENT SOCIAL
Zdroj: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 12:290-292
ISSN: 1077-9450
DOI: 10.1097/00042560-199607000-00009
Popis: To investigate the potential acceptability of interventions intended to reduce mother-to-child transmission of human immunodeficiency virus (HIV)-1 in West Africa a pilot study was conducted among 607 pregnant women at maternal-child health centers in Abidjan (Ivory Coast) and Bobo-Dioulasso (Burkina Faso). 81-95% of women interviewed at the 4 sites accepted the principle of an HIV screening test and 92-97% indicated they would want to know the results. However 64-91% stated they would need the consent of their partner before testing. In the event of a positive test result most women were agreeable to participation in an intervention (i.e. oral tablets vaginal suppositories both tablets and suppositories) aimed at reducing the risk of HIV-1 transmission to their infant. The option chosen by the most women varied according to study site. Finally when the concept of a double-blind randomized placebo-controlled clinical trial was explained by a social worker to women at the 2 sites in Bobo-Dioulasso 87% and 90% found this acceptable. Although these results do not necessarily predict the actual behaviors of pregnant women in a situation to be enrolled in clinical trials the results are sufficiently promising to suggest that affordable sustainable and appropriate interventions for reducing maternal transmission of HIV-1 should be evaluated in Africa.
Databáze: OpenAIRE
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