Gout in the Axial Skeleton
| Autor: | Rukmini M. Konatalapalli, Bryan T. Jennings, Michael S. Gibson, Mark D. Murphey, James S. Jelinek, Arthur Weinstein, Paul J. Demarco |
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| Rok vydání: | 2009 |
| Předmět: |
Male
musculoskeletal diseases medicine.medical_specialty Axial skeleton Gout Appendicular skeleton Immunology Lumbar vertebrae Facet joint Cohort Studies Rheumatology Internal medicine Pars interarticularis Prevalence medicine Humans Immunology and Allergy Aged Retrospective Studies Aged 80 and over business.industry Middle Aged medicine.disease Spine Epidural space medicine.anatomical_structure District of Columbia Female Radiology Tomography X-Ray Computed business |
| Zdroj: | The Journal of Rheumatology. 36:609-613 |
| ISSN: | 1499-2752 0315-162X |
| Popis: | Objective.Gout typically affects the peripheral joints of the appendicular skeleton and rarely involves the axial joints. The literature on axial gout is limited to case reports and case series. This preliminary study was conducted to identify the frequency and characteristics of axial gout.Methods.Six hundred thirty medical records with ICD codes 274.0, 274.82, and 274.9 for peripheral gout were reviewed. Ninety-two patients had clinical or crystal-proven gout, of which 64 had prior computed tomography (CT) images of the spine performed for various medical reasons. These CT images were reviewed for features of axial gout, which include vertebral erosions mainly at the discovertebral junction and the facet joints, deposits of tophi, and erosions in the vertebral body, epidural space, ligamentum flavum and pars interarticularis.Results.Nine of the 64 patients had radiographic changes suggestive of axial gout. Lumbar vertebrae were most commonly involved, with facet joint erosions being the most common finding. Isolated involvement of the sacroiliac joints was seen in 2 patients. Axial gout had been diagnosed clinically in only one patient.Conclusion.Radiologic changes of axial gout were more common than recognized clinically, with a frequency of 14%. Since not all patients had CT images, it is possible that the frequency of axial involvement was even greater. A prospective study is needed to further define this process. |
| Databáze: | OpenAIRE |
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