Suppressed circadian heart rate dynamics in temporal lobe epilepsy
Autor: | Hanna Ansakorpi, Juha T. Korpelainen, Jouko I. T. Isojärvi, E Ronkainen, Vilho V. Myllylä, Heikki V. Huikuri |
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Rok vydání: | 2005 |
Předmět: |
Adult
Male Paper medicine.medical_specialty Severity of Illness Index behavioral disciplines and activities Temporal lobe Central nervous system disease Electrocardiography Epilepsy Heart Rate Internal medicine Severity of illness Heart rate medicine Humans Ictal Circadian rhythm medicine.diagnostic_test medicine.disease Circadian Rhythm nervous system diseases Psychiatry and Mental health Endocrinology Epilepsy Temporal Lobe nervous system Cardiology Anticonvulsants Female Surgery Neurology (clinical) Psychology psychological phenomena and processes |
Zdroj: | Journal of Neurology, Neurosurgery & Psychiatry. 76:1382-1386 |
ISSN: | 0022-3050 |
Popis: | To measure interictal circadian rhythm of heart rate (HR) variability in patients with temporal lobe epilepsy (TLE) using a 24 hour ECG recording.Various conventional and dynamic fractal measures of HR variability were analysed in 17 patients with refractory TLE, 20 patients with well controlled TLE, and 37 healthy age and sex matched control subjects.The SD of all RR intervals (p0.01), the measured power spectral components of HR variability (low frequency power (p0.01), high frequency power (p0.05)), and the SD1 (p0.05) and SD2 (p0.01) Poincaré two dimensional vector analysis measurements were suppressed in the patients. This suppression was observed during both day and night time; however, it was more pronounced at night, and nocturnal increase in HR variability usually seen in the normal population could not be detected in the patients. The HR variability measures did not correlate with the duration of epilepsy, the age of the patients, or with the anti-epileptic drugs used.TLE was associated with reduced HR variability, which was more pronounced during night than day, and the nocturnal increase in HR variability was abolished in patients with TLE. The alteration in autonomic regulation of HR variability was similar in patients with both refractory and well controlled TLE. |
Databáze: | OpenAIRE |
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