Bicuculline infusion into the accessory olfactory bulb facilitates the induction of maternal behavior in rats

Autor:	M.C.R. Del Cerro, F. Gómez, Santiago Segovia, M. I. Carretero
Rok vydání:	2003
Předmět:	medicine.medical_specialty Vomeronasal organ Convulsants Olfaction Bicuculline Arts and Humanities (miscellaneous) Internal medicine Developmental and Educational Psychology medicine Animals Rats Wistar Maternal Behavior Inhibitory effect Infusion Pumps General Psychology GABAA receptor Antagonist General Medicine Accessory Olfactory Bulb Olfactory Bulb Rats Endocrinology Female Psychology medicine.drug
Zdroj:	Scandinavian Journal of Psychology. 44:273-277
ISSN:	1467-9450 0036-5564
Popis:	The GABAA antagonist bicuculline, intracranially infused into the accessory olfactory bulb (AOB), facilitated the expression of maternal behavior (MB) in virgin Wistar female rats. Behavioral effects were observed 24 hours after infusion and were injection dependent. Pheromonal stimuli, generated by the pups, are thought to exert an inhibitory effect on vomeronasal nuclei involved in MB in virgin rats. The present study investigated the possibility that a decrement in AOB output, resulting from long-term compensatory synaptic changes to chronic bicuculline infusion, would facilitate the expression of MB. The implications of our findings for the mechanisms involved in the induction of MB and the maternal experience effect are discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be02cbe83411b49e4923c84343db4363 https://doi.org/10.1111/1467-9450.00345 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.