Equine Multinodular Pulmonary Fibrosis in association with asinine herpesvirus type 5 and equine herpesvirus type 5: a case report
| Autor: | Rodrigo Grandon, Anna Kendall, Karl Ståhl, Karin Ullman, John Pringle, Louise Treiberg-Berndtsson, Helena Back |
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| Jazyk: | angličtina |
| Předmět: |
Male
Pathology medicine.medical_specialty Pulmonary Fibrosis Case Report DNA-Directed DNA Polymerase Lung biopsy Horse Polymerase Chain Reaction EHV-5 Fatal Outcome Gammaherpesvirinae Species Specificity Pulmonary fibrosis Biopsy medicine Animals Horses Leukocytosis Lung Sweden lcsh:Veterinary medicine General Veterinary biology medicine.diagnostic_test business.industry Herpesviridae Infections General Medicine AHV-5 Clinical Science biology.organism_classification medicine.disease Equine Multinodular Pulmonary Fibrosis Pathobiology Pneumonia medicine.anatomical_structure lcsh:SF600-1100 Horse Diseases medicine.symptom Equine herpesvirus business |
| Zdroj: | Acta Veterinaria Scandinavica, Vol 54, Iss 1, p 57 (2012) Acta Veterinaria Scandinavica |
| ISSN: | 1751-0147 |
| DOI: | 10.1186/1751-0147-54-57 |
| Popis: | A standardbred gelding with a history of 10 days pyrexia and lethargy was referred to the Equine Hospital at the Swedish University of Agricultural Sciences in Uppsala, Sweden. The horse had tachypnea with increased respiratory effort and was in thin body condition. Laboratory findings included leukocytosis, hyperfibrinogenemia and hypoxemia. Thoracic radiographs showed signs of pneumonia with a multifocal nodular pattern, which in combination with lung biopsy findings indicated Equine Multinodular Pulmonary Fibrosis (EMPF). EMPF is a recently described disease in adult horses with clinical signs of fever, weight loss and respiratory problems. The pathological findings include loss of functional pulmonary parenchyma due to extensive nodular interstitial fibrosis which has been related to infection with the equine herpesvirus type 5 (EHV-5). In this case, lung biopsy and tracheal wash samples tested positive for both asinine herpesvirus type 5 (AHV-5) and EHV-5 using PCR assays. The horse failed to respond to treatment and was euthanized for humane reasons. Postmortem examination confirmed the diagnosis of EMPF. This case suggests that not only EHV-5 alone should be considered in association with the development of this disease. |
| Databáze: | OpenAIRE |
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