Types of errors on a semantic interference task in mild cognitive impairment and dementia
| Autor: | William W. Barker, Monica Rosselli, Ranjan Duara, Valeria L. Torres, Idaly Vélez Uribe, Merike Lang, Maria T. Greig, Russell M. Bauer, Ailyn Penate, Rosie E. Curiel, David E. Vaillancourt, David A. Loewenstein, Fernanda Arruda |
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| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty PsycINFO Neuropsychological Tests Audiology Semantics Article 050105 experimental psychology Task (project management) Intrusion Qualitative analysis mental disorders medicine Humans Learning Dementia Attention Cognitive Dysfunction 0501 psychology and cognitive sciences Cognitive impairment Aged 05 social sciences Cognition medicine.disease Neuropsychology and Physiological Psychology Female Psychology |
| Zdroj: | Neuropsychology |
| ISSN: | 1931-1559 0894-4105 |
| Popis: | Objective This research aimed to determine whether qualitative analysis of different types of intrusion errors on a verbal cognitive task was useful in detecting subtle cognitive impairment in preclinical stages prior to the progression to dementia. Method Different types of semantic intrusions on the Loewenstein-Acevedo Scales of Semantic Interference and Learning (LASSI-L) were compared across 160 individuals diagnosed as cognitively normal (CN), amnestic Mild Cognitive Impairment (aMCI), and dementia. The sample included Hispanics and non-Hispanic European Americans. Results Across diagnostic groups, the most common type of intrusion error was actual targets presented from a competing word list under conditions eliciting proactive semantic interference (PSI), and retroactive semantic interference (RSI), followed by intrusions that represented one of three overlapping semantic categories but none of the targets from List A or B. Nonsemantic intrusions rarely occurred. These competing list intrusions (CLI) and semantically related intrusions (SRI) differentiated between aMCI and CN participants. Further, these intrusion error were related to brain amyloid load, indicating their importance as potential primary markers of AD-related neurodegeneration. Ethnicity effects were not seen across the types of intrusion errors. Conclusions Two types of intrusion errors (CLI and SRI) showed differences between the CN and aMCI group, with the aMCI group evidencing a higher rate of these intrusion errors compared with the CN group. These results support previous literature about the LASSI-L's sensitivity at the earliest stages of abnormal aging. (PsycINFO Database Record (c) 2019 APA, all rights reserved). |
| Databáze: | OpenAIRE |
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