Investigation of Chlamydia pneumoniae infection in Moroccan patients suffering from cardiovascular diseases
| Autor: | Hicham Hejaji, Naima Elmdaghri, Nadia Dakka, Fouzia Radouani, Loubna El Yazouli, Aziz Aroussi Alami |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
DNA
Bacterial Male 0301 basic medicine medicine.medical_specialty Disease 030204 cardiovascular system & hematology medicine.disease_cause Polymerase Chain Reaction Peripheral blood mononuclear cell lcsh:Infectious and parasitic diseases 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine Prevalence Humans Medicine lcsh:RC109-216 Respiratory system Risk factor Chlamydophila Infections Dominance (genetics) Chlamydia business.industry lcsh:Public aspects of medicine Public Health Environmental and Occupational Health lcsh:RA1-1270 General Medicine Chlamydophila pneumoniae Middle Aged Atherosclerosis medicine.disease Antibodies Bacterial 030104 developmental biology Infectious Diseases Atheroma Molecular Diagnostic Techniques Cardiovascular Diseases Immunology Leukocytes Mononuclear Female business |
| Zdroj: | Journal of Infection and Public Health, Vol 11, Iss 2, Pp 246-249 (2018) |
| ISSN: | 1876-0341 |
| Popis: | Chlamydia pneumoniae is an intracellular bacterium responsible for respiratory diseases and is highly involved in cardiovascular disease development, mainly atherosclerosis.The main objective of our study was to evaluate C. pneumoniae prevalence in Moroccan patients suffering from cardiovascular diseases. A total of 115 patients with cardiovascular diseases were enrolled, and their clinical and behavioral information was recorded. Blood was sampled from all patients as well as the atheroma plaques from 36 patients undergoing surgery. Nested PCR was performed for C. pneumoniae DNA detection in both peripheral blood mononuclear cells (PBMCs) and atheroma plaques. Statistical analysis was performed using EpiInfo software.Data analysis showed cardiovascular disease dominance in men, with a sex ratio M/F of 3.4, a majority of tobacco users (52.2%), and many diabetics (44.3%). A significant difference between genders was shown for tobacco use (p |
| Databáze: | OpenAIRE |
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