Formation and utility of reactive ketene intermediates under continuous flow conditions

Autor:	Duncan L. Browne, Harry R. Smallman, Tom McBride, Jamie A. Leitch, Steven V. Ley
Přispěvatelé:	Smallman, HR [0000-0002-0665-4967], Leitch, JA [0000-0001-6997-184X], McBride, T [0000-0001-8200-7676], Apollo - University of Cambridge Repository
Rok vydání:	2021
Předmět:	Reactive intermediates Photochemistry 010405 organic chemistry Continuous flow Organic Chemistry Reactive intermediate Ketene Acyl-ketene 010402 general chemistry 01 natural sciences Biochemistry 0104 chemical sciences chemistry.chemical_compound chemistry Drug Discovery Reactivity (chemistry)
Zdroj:	Tetrahedron. 93:132305
ISSN:	0040-4020
DOI:	10.1016/j.tet.2021.132305
Popis:	Continuous flow systems offer unique benefits in the generation and manipulation of sensitive reactive intermediates such as ketenes. To this end, the last decade has witnessed the development of continuous flow methods for the generation of ketenes by means of chemical, thermal, and photochemical activation modes. This perspective covers these advances and the downstream reactivity of ketenes in continuous flow technology.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdefd7b3e4d2ba554efdbe9bb786d18f https://doi.org/10.1016/j.tet.2021.132305 Zobrazit plný text záznamu Full Text from ScienceDirect