Impact of depression on clinical outcomes following percutaneous coronary intervention: a systematic review and meta-analysis
| Autor: | Xian Tao Song, Nan Nan, Wen Yi Zhang, Jin Fan Tian, Xue Yao Yang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment lcsh:Medicine Coronary Artery Disease PsycINFO CINAHL Cardiovascular Medicine Postoperative Complications Risk Factors Internal medicine Outcome Assessment Health Care Systematic risk medicine Humans Prospective cohort study Depression (differential diagnoses) Depression business.industry Research percutaneous coronary intervention lcsh:R Percutaneous coronary intervention General Medicine Prognosis meta-analysis Meta-analysis Conventional PCI business |
| Zdroj: | BMJ Open, Vol 9, Iss 8 (2019) BMJ Open |
| ISSN: | 2044-6055 |
| Popis: | ObjectivesThe objective of this meta-analysis was to assess whether depression in percutaneous coronary intervention (PCI) patients is associated with higher risk of adverse outcomes.DesignSystematic review and meta-analysis.MethodsEMBASE, PubMed, CINAHL and PsycINFO were searched as data sources. We selected prospective cohort studies evaluating the relationship between depression and any adverse medical outcome, including all-cause mortality, cardiac mortality and non-fatal events, from inception to 28 February 2019. Two reviewers independently extracted information and calculated the risk of cardiovascular events in patients with preoperative or postoperative depression compared with non-depressed patients.ResultsEight studies (n=3297) met our inclusion criteria. Most studies found a positive association between depression and adverse cardiovascular outcomes. Meta-analysis yielded an aggregate risk ratio of 1.57 (95% CI 1.28 to 1.92, pConclusionsOur systematic review and meta-analysis suggests that depression is associated with an increased risk of worse clinical outcome or mortality in patients undergoing PCI. Assessment time and length of follow-up do not have a significant effect on this conclusion. |
| Databáze: | OpenAIRE |
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