[Lifetime Psychiatric Disorders: a Comparision Study Between Offspring of Parents With Bipolar Disorder Type-I Versus the Offspring of Community Controls Parents]
| Autor: | María Alejandra Gómez-Valero, Juan David Palacio-Ortiz, Carlos López-Jaramillo, Paula Andrea Bustamante-Gómez, Cristian Esteban Peña-Quintero, Cristian David Vargas-Upeguí, Pilar Helena Arroyave-Sierra |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Bipolar Disorder Adolescent Offspring Cross-sectional study Bipolar disorder not otherwise specified Interviews as Topic 03 medical and health sciences Young Adult 0302 clinical medicine Child of Impaired Parents medicine Prevalence Humans Bipolar disorder Young adult Psychiatry Child General Environmental Science Psychiatric Status Rating Scales Mental Disorders Middle Aged medicine.disease Confidence interval 030227 psychiatry Cross-Sectional Studies General Earth and Planetary Sciences Major depressive disorder Female Psychology 030217 neurology & neurosurgery Psychopathology Clinical psychology |
| Zdroj: | Revista colombiana de psiquiatria. 46(3) |
| ISSN: | 0034-7450 |
| Popis: | Introduction Literature reports show that bipolar offspring (BO) present with a wide range of psychiatric disorders. Comparison between BO and control parent offspring (CPO) may help to identify which psychopathological findings are specific to this high-risk group. Objective To compare the psychopathological characteristics between a group of BO type- I and a group of CPO, by identifying the presence of psychiatric disorders according the DSM- IV -TR. Methods A descriptive-correlational, cross-sectional and comparative study was conducted with 127 offspring of parents with bipolar disorder type- I from the multimodal intervention programme (PRISMA) and with 150 CPO between 6 and 30 years of age. Subjects were evaluated with validated diagnostic interviews (K-SADS-PL and DIGS). Results The BO group showed higher frequencies for bipolar disorder (prevalence ratio [PR] = 17.70; 95% confidence interval [CI]; 1.02–306.83), bipolar disorder not otherwise specified (PR = 23.07, 95% CI; 2.8–189.0, p = 0.0001), disorders due to psychoactive substance use (PR = 9.52, 95% CI; 2.93–30.90), oppositional defiant disorder (PR = 4.10, 95% CI; 1.70–9.89), posttraumatic stress disorder (PR = 3.90, 95% CI 1.30–11.66), disorder due to alcohol use (PR = 3.84, 95% CI; 1.28–11.48), attention deficit/hyperactivity disorder (PR = 2.26, 95% CI; 1.37–3.75), and major depressive disorder (PR = 2.25, 95% CI; 1.13–4.50). Statistically significant differences were also found in the CGAS and GAF functional scales, with lower scores for the BO group. Conclusion These findings confirm previous literature reports showing that BO have higher rates of affective and non-affective psychiatric disorders than control subjects, and also a lower level of global functioning. |
| Databáze: | OpenAIRE |
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