| Autor: |
Luigi Moriconi, Gabriella Paleologo, Luigi Bedini, Leopoldo Cioni |
| Rok vydání: |
1979 |
| Předmět: |
|
| Zdroj: |
La Ricerca in clinica e in laboratorio. 9(4) |
| ISSN: |
0390-5748 |
| Popis: |
Seventy-five biopsy samples from patients with chronic renal disorders were examined by the usual techniques of light microscopy and immunofluorescence; in fifteen patients IgA nephropathy was found. These patients were young adults; the onset of the disease was characterized by macrohematuria, and recurrent episodes of hematuria were observed. Histological examination revealed proliferative endothelio-mesangial glomerulonephritis at various stages of development with focal or diffuse patterns; immunofluorescence revealed constant and intense positive reactions for IgA mainly in association with C3. It is assumed that there is a relationship connecting the more advanced histological changes, a more severe clinical course and the presence of IgM deposits. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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