Prediktori ranog nastupa depresije nakon moždanog udara

Autor: Vlado Đajić, Tamara Rabi-Žikić, Željko Živanović, Svetlana Ružička-Kaloci, Sonja Slankamenac, Svetlana Simić, Milorad Žikić
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Acta Clinica Croatica, Vol 59, Iss 1., Pp 81-90 (2020)
Acta clinica Croatica
Volume 59.
Issue 1.
Acta Clinica Croatica
ISSN: 1333-9451
0353-9466
Popis: Post-stroke depression (PSD) is a severe and frequent stroke complication and one of the crucial factors for the outcome of rehabilitation and life quality after stroke. However, mood disorders frequently remain unnoticed and therefore untreated. The aim of the study was to examine all the potential risk factors and determine the independent predictors of early-onset depression after first-ever stroke, which would help identify high-risk patients, establish early diagnosis and timely treatment that would improve the course and prognosis of this disorder. This prospective study included 60 patients treated for their first-ever stroke; there were 30 patients diagnosed with depression and 30 patients without depression. The study included collection and analysis of all socio-demographic and clinical risk factors for PSD. Testing was performed two weeks after stroke. Depression was diagnosed according to the Mini International Neuropsychiatry Interview, DSM-IV diagnostic criteria, and depression severity was quantified by the Hamilton Depression Rating Scale. Cognitive impairment was assessed by the Mini Mental State Examination. Neurological deficit was assessed by the US National Institute of Health Stroke Scale. Our results showed that the independent predictors of early-onset depression after stroke were previous depressive episodes, cognitive dysfunction, and more severe neurological deficit.
Depresija nakon moždanog udara je teška i česta komplikacija moždanog udara i jedan od ključnih čimbenika za ishod rehabilitacije i kvalitetu života nakon moždanog udara. Međutim, poremećaji raspoloženja ostaju najčešće neprepoznati, a samim tim i neliječeni. Cilj ovoga istraživanja bio je ispitati sve potencijalne čimbenike rizika i utvrditi nezavisne prediktore depresije koja se javlja rano nakon moždanog udara, a koji bi omogućili identifikaciju visokorizičnih bolesnika, postavljanje rane dijagnoze i pravodobno liječenje, što bi unaprijedilo tijek i prognozu ove bolesti. Prospektivno istraživanje obuhvatilo je 60 bolesnika liječenih zbog klinički prvog moždanog udara, od toga 30 bolesnika s dijagnosticiranom depresijom i 30 bolesnika bez depresije. Istraživanje je obuhvatilo podatke o svim socio-demografskim i kliničkim čimbenicima rizika za nastanak depresije nakon moždanog udara. Testiranja su provedena dva tjedna nakon moždanog udara. Depresija je dijagnosticirana prema Mini International Neuropsychiatry Interview, DSM-IV dijagnostičkim kriterijima, težina depresije kvantificirana je Hamiltonovom ljestvicom za procjenu depresivnosti (HDRS). Kognitivni status procjenjivao se pomoću Mini Mental State Examination (MMSE). Neurološki status se procjenjivao pomoću Ljestvice za moždani udar Nacionalnog instituta za zdravlje, SAD (NIHSS). Rezultati našega istraživanja ukazuju na to da su nezavisni prediktori ranog nastupa depresije nakon moždanog udara ranije depresivne epizode, kognitivne disfunkcije i teži neurološki deficit.
Databáze: OpenAIRE
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