Delayed Breast Implant Reconstruction
| Autor: | Tine Engberg Damsgaard, Loren Lipworth, Gitte B. Hvilsom, Joseph K. McLaughlin, Marianne Steding-Jessen, Jens Jørgen Elberg, Trine Henriksen, Kirsten Frederiksen, Søren Friis, Lisbet Rosenkrantz Hölmich |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Reoperation medicine.medical_specialty Time Factors Breast Implants Denmark Mammaplasty Breast surgery medicine.medical_treatment Breast Neoplasms Comorbidity law.invention Cohort Studies Risk Factors law Implant Capsular Contracture medicine Humans Breast Registries Breast Implantation Proportional Hazards Models Radiotherapy Proportional hazards model business.industry Hazard ratio Capsular contracture Surgery Causality Radiation therapy Plastic surgery Breast implant Female Radiology Breast reconstruction business |
| Zdroj: | Hvilsom, G B, Hölmich, L R, Steding-Jessen, M, Frederiksen, K, Henriksen, T F, Lipworth, L, McLaughlin, J K, Elberg, J J, Damsgaard, T E & Friis, S 2012, ' Delayed breast implant reconstruction : Is radiation therapy associated with capsular constracture or reoperations ', Annals of Plastic Surgery, vol. 68, no. 3, pp. 246-252 . https://doi.org/10.1097/SAP.0b013e318214e69c |
| ISSN: | 0148-7043 |
| Popis: | We evaluated the association between radiation therapy and severe capsular contracture or reoperation after 717 delayed breast implant reconstruction procedures (288 1- and 429 2-stage procedures) identified in the prospective database of the Danish Registry for Plastic Surgery of the Breast during the period between 1999 and 2006. A history of radiation therapy was associated with increased risk of severe capsular contracture for 1- and 2-stage procedures, with adjusted hazard ratios (HR) of 3.3 (95% confidence interval [CI]: 0.9-12.4) and 7.2 (95% CI: 2.4-21.4), respectively. Similarly, a history of radiation therapy was associated with a non-significantly increased risk of reoperation after both 1-stage (HR = 1.4; 95% CI: 0.7-2.5) and 2-stage (HR = 1.6; 95% CI: 0.9-3.1) procedures. Reconstruction failure was highest (13.2%) in the 2-stage procedures with a history of radiation therapy. Breast reconstruction approaches other than implants should be seriously considered among women who have received radiation therapy. |
| Databáze: | OpenAIRE |
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