Factors associated with behavioral problems and cognitive impairment in children with epilepsy of Kinshasa, Democratic Republic of the Congo
| Autor: | Thierry Matonda-ma-Nzuzi, Magloire Nkosi Mpembi, Davin Mpaka Mbeya, Michel Ntentani Aloni, Fanny Malendakana, Diane Muanza Mvumbi, Dominique Charlier-Mikolajczak, Samuel Mampunza Ma Miezi, Gilbert Mananga Lelo |
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| Přispěvatelé: | UCL - SSS/IRSS - Institut de recherche santé et société, UCL - (SLuc) Service de psychiatrie infanto-juvénile |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Male
Multivariate analysis Adolescent Context (language use) Behavioral Symptoms Child Behavior Disorders Comorbidity Behavioral problems Developmental psychology 03 medical and health sciences Behavioral Neuroscience Epilepsy Nonverbal communication 0302 clinical medicine Seizures 030225 pediatrics medicine Humans Cognitive Dysfunction Cognitive impairment Child Behavior Checklist Child Socioeconomic status Children Problem Behavior Sub-Saharan Africa business.industry Wechsler Adult Intelligence Scale medicine.disease Cross-Sectional Studies Neurology Socioeconomic Factors Democratic Republic of the Congo Anticonvulsants Female Neurology (clinical) business Cognition Disorders 030217 neurology & neurosurgery Clinical psychology |
| Zdroj: | Epilepsy & Behavior, Vol. 78, p. 78-83 (2018) |
| Popis: | Background Behavioral problems and cognitive impairment are common in children with epilepsy (CWE). In sub-Saharan Africa, little is known about these comorbidities particularly their relationships with socioeconomic features. The goal of this study was to identify clinical and socioeconomic factors associated with behavioral problems and cognitive impairment in CWE of Kinshasa (Democratic Republic of the Congo). Methods This cross-sectional hospital-based study had included 104 CWE aged 6 to 17 years. Behavioral problems were assessed by the child behavior checklist. The Wechsler nonverbal scale of ability was used to assess cognitive impairment. Results At least one behavioral problem was found in 34.6% of CWE. Internalized problems were increasing with father’s age (p = 0.034). Externalized problems were increasing with the decreased of mother’s age (p = 0.009) and with a previous antiepileptic treatment (p = 0.032). Total behavioral problems were increasing with a previous antiepileptic treatment (p = 0.029). Cognitive impairment was present in 73.3% of CWE. It was more common in boys (p = 0.013), and it was increasing with a low household daily expenses (p = 0.034), with a previous antiepileptic treatment (p = 0.041), with an early onset of epileptic seizures (p = 0.042), and with a high frequency of epileptic seizures (p = 0.011). Conclusion Behavioral problems and cognitive impairment are common in CWE. Multivariate analysis has shown that behavioral problems were associated with socioeconomic features only. Contrariwise, cognitive impairment was associated with both socioeconomic factors and clinical features. There is a need of more studies to improve knowledge of these comorbidities in the sub-Saharan Africa context. |
| Databáze: | OpenAIRE |
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