Inhibition of mouse mammary carcinoma development with doxorubicin in liposomes
| Autor: | Jan Vaage, Peter Working, Paul Uster |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Cancer Research
Pathology medicine.medical_specialty medicine.medical_treatment Mammary gland Drug Administration Schedule Mammary carcinoma Mice In vivo Carcinoma medicine Animals Doxorubicin Chemotherapy Liposome Drug Carriers Mice Inbred C3H Antibiotics Antineoplastic business.industry Mammary Neoplasms Experimental medicine.disease medicine.anatomical_structure Oncology Liposomes Cancer research Female Drug carrier business medicine.drug |
| Zdroj: | International journal of cancer. 75(1) |
| ISSN: | 0020-7136 |
| Popis: | Monthly treatments with intravenous doxorubicin encapsulated in long circulating, sterically stabilized liposomes delayed the appearance of primary mammary carcinomas and reduced the final incidence from 49 in 50 untreated mice to 46 in 87 treated mice. No toxic side effects of the treatments were observed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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