SARS‐CoV‐2 and lung injury: Dysregulation of immune response but not hyperimmune response as in 'cytokine storm syndrome'
| Autor: | Serpil Öcal |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Pulmonary and Respiratory Medicine
ARDS dysregulation of immune response Mini Review critically ill patients Acute Lung Injury Mini Reviews Lung injury Asymptomatic SARS‐CoV‐2 Hypoxemia Immune system medicine Humans Immunology and Allergy Genetics (clinical) SARS-CoV-2 business.industry fungi Confounding Immunity COVID-19 respiratory system medicine.disease respiratory tract diseases ALI Viral pneumonia Immunology medicine.symptom Cytokine Release Syndrome Cytokine storm business |
| Zdroj: | The Clinical Respiratory Journal |
| ISSN: | 1752-699X 1752-6981 |
| Popis: | SARS‐CoV‐2 infection can present either an asymptomatic or symptomatic; the spectrum of symptomatic infection ranges from mild to critical. A majority of patients have experienced mild symptoms with a good prognosis. But approximately 14% of them have severe infection presenting with hypoxemia and extensive lung involvement. The current mini‐review describes the dysregulation of immune response for SARS‐CoV‐2 viral pneumonia and virus‐induced lung injury. Also, many confounding factors can increase lung injury, in addition to virus‐induced lung injury. Especially in critically ill patients, confounding factors can cause the inflammatory cascade, acute respiratory distress syndrome (ARDS), and mortality. |
| Databáze: | OpenAIRE |
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