The Antigastric Cancer Activity of San Leng Powder Extract Induces Apoptosis in Balb/C Bearing-SGC-7901 Mice

Autor: Yu Sun, Chen Yu, Shi-Jia Liu, Jian-Wei Lu, Ai-Jun Ji
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Evidence-Based Complementary and Alternative Medicine, Vol 2017 (2017)
Evidence-based Complementary and Alternative Medicine : eCAM
ISSN: 1741-4288
Popis: San Leng powder extract has been used as medicinal compound for the prevention and treatment of cancers. The antitumor activity of SLPE was determined by treating BALB/C mice harboring a human gastric cancer xenograft with SPLE for 17 days. Mice were also treated with fluorouracil (5-Fu, 25 mg/kg) or a combination of SLPE and 5-Fu. Our results indicate that the inhibition of tumor growth by SLPE might be due to a block in the cell cycle and the induction of apoptosis. These results suggest that SLPE might be useful in the treatment of gastric cancer.
Databáze: OpenAIRE