The Antigastric Cancer Activity of San Leng Powder Extract Induces Apoptosis in Balb/C Bearing-SGC-7901 Mice
Autor: | Yu Sun, Chen Yu, Shi-Jia Liu, Jian-Wei Lu, Ai-Jun Ji |
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Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: |
0301 basic medicine
Antitumor activity Article Subject biology Chemistry Cancer lcsh:Other systems of medicine Cell cycle Pharmacology biology.organism_classification medicine.disease lcsh:RZ201-999 BALB/c 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Complementary and alternative medicine Fluorouracil Apoptosis 030220 oncology & carcinogenesis medicine Tumor growth medicine.drug Research Article |
Zdroj: | Evidence-Based Complementary and Alternative Medicine, Vol 2017 (2017) Evidence-based Complementary and Alternative Medicine : eCAM |
ISSN: | 1741-4288 |
Popis: | San Leng powder extract has been used as medicinal compound for the prevention and treatment of cancers. The antitumor activity of SLPE was determined by treating BALB/C mice harboring a human gastric cancer xenograft with SPLE for 17 days. Mice were also treated with fluorouracil (5-Fu, 25 mg/kg) or a combination of SLPE and 5-Fu. Our results indicate that the inhibition of tumor growth by SLPE might be due to a block in the cell cycle and the induction of apoptosis. These results suggest that SLPE might be useful in the treatment of gastric cancer. |
Databáze: | OpenAIRE |
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