Familial hyperthyroidism including two siblings with neonatal Graves' disease
| Autor: | Robert S. Wilroy, James N. Etteldorf |
|---|---|
| Rok vydání: | 1971 |
| Předmět: |
Adult
Male endocrine system Pediatrics medicine.medical_specialty Adolescent endocrine system diseases Graves' disease Disease Hyperthyroidism Infant Newborn Diseases Craniosynostosis Fingers Craniosynostoses Intellectual Disability medicine Humans Euthyroid Child Bone Development business.industry Thyroid Infant Newborn Infant Acropachy medicine.disease Graves Disease Pedigree Surgery Long-Acting Thyroid Stimulator medicine.anatomical_structure Propylthiouracil Child Preschool Pediatrics Perinatology and Child Health Neonatal Graves Disease Female business |
| Zdroj: | The Journal of Pediatrics. 78:625-632 |
| ISSN: | 0022-3476 |
| DOI: | 10.1016/s0022-3476(71)80464-x |
| Popis: | A Negro family is reported in which 4 members of 3 generations suffered from Graves' disease. Two premature siblings, born a year apart, whose mother had Graves' disease, had persistent neonatal thyrotoxicosis. Their bone ages advanced rapidly and each developed craniosynostosis. Antithyroid medication was given for several years. Long-acting thyroid stimulator assays were elevated at ages 8 and 9 years, respectively, but were normal 7 years later. Although these children have remained euthyroid at 15 and 16 years, respectively, they are mentally subnormal and have developed acropachy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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