Peripheral nervous system and spinal cord involvement in lymphoma
| Autor: | E. G. Reich, J. Correale, J. A. Bueri, D. A. Monteverde |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Paraneoplastic Syndromes medicine.medical_treatment Splenectomy Opportunistic Infections Herpes Zoster Gastroenterology Spinal Cord Diseases Internal medicine Antineoplastic Combined Chemotherapy Protocols Humans Medicine Prospective Studies Aged Retrospective Studies Neurologic Examination Chemotherapy business.industry Lymphoma Non-Hodgkin Nerve Compression Syndromes Peripheral Nervous System Diseases General Medicine Middle Aged medicine.disease Spinal cord Hodgkin Disease Surgery Discontinuation Lymphoma Peripheral neuropathy medicine.anatomical_structure Neurology Vincristine Peripheral nervous system Female Neurology (clinical) Spinal Nerve Roots Complication business Spinal Cord Compression Follow-Up Studies |
| Zdroj: | Acta Neurologica Scandinavica. 83:45-51 |
| ISSN: | 1600-0404 0001-6314 |
| DOI: | 10.1111/j.1600-0404.1991.tb03957.x |
| Popis: | Nine-hundred-eighty-nine patients with diagnosis of lymphoma were studied. Forty-six cases (4.6%) had compressions of the spinal cord or roots. Forty-two patients (4.2%) had Herpes zoster virus infections, which in 6 cases were of disseminated type. The major predisposing factors for infection were: advanced stage of lymphoma, previous systemic chemotherapy and splenectomy. Toxic polyneuropathy secondary to chemotherapy was found in 39 patients (3.9%). In 14 cases, the polyneuropathic symptoms were the main complaint (Group 1), while in the remaining 25 cases the diagnosis was made during neurological consultations because of unrelated symptoms (Group 2). Both groups did not have significant differences in the total dose of chemotherapy received. The electrophysiological studies showed an axonal neuropathy in both groups. The discontinuation of chemotherapy was found to be a limiting factor in the appearance of neuropathic symptoms. Other less frequent forms of involvement were: compression of peripheral nerves or nerve plexi from lymphadenopathies (3 cases), radiation myelopathy (1 case), and Guillain-Barré Syndrome associated with Hodgkin's Lymphoma (1 case). |
| Databáze: | OpenAIRE |
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