Abnormal left ventricular filling with increasing age reflects abnormal myocardial characteristics independent of ischemia or hypertrophy
| Autor: | Satoshi Yuda, Leanne Short, Rodel Leano, Thomas H. Marwick |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Male
medicine.medical_specialty Ischemia Doppler echocardiography Doppler imaging Ventricular Function Left Muscle hypertrophy Coronary artery disease Internal medicine medicine Humans Pressure overload Chi-Square Distribution Cardiac cycle medicine.diagnostic_test business.industry Myocardium Age Factors Reproducibility of Results Middle Aged medicine.disease Logistic Models Echocardiography Parasternal line Cardiology Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | The American Journal of Cardiology. 91:63-67 |
| ISSN: | 0002-9149 |
| DOI: | 10.1016/s0002-9149(02)02999-5 |
| Popis: | Abnormal left ventricular (IV) filling may occur with increasing age despite apparently normal IV size and function, and is usually attributed to IV hypertrophy and coronary artery disease. The purpose of this study was to determine whether myocardial abnormalities could be identified in 67 such patients (36 men, mean age 57 +/- 9 years) whose IV hypertrophy and coronary artery disease were excluded by dobutamine echocardiography. All patients underwent gray scale and color tissue Doppler imaging from 3 apical views, which were stored and analyzed off line. Disturbances in structure and function were assessed by averaging the cyclic variation of integrated backscatter, strain rate, and peak systolic strain from each myocardial segment. Calibrated integrated backscatter (corrected for pericardial backscatter intensity) was measured in the septum and posterior wall from the parasternal long-axis view. Abnormal IV filling was present in 36 subjects (54%). Subjects with and without abnormal IV filling had similar IV mass, but differed in age (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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