Reflectivity of the outer retina on spectral-domain optical coherence tomography as a predictor of photoreceptor cone density
| Autor: | Perle Tumahai, Mathieu Flores, Guillaume Debellemanière, M Meillat, Bernard Delbosc, Alois Bully, Maher Saleh |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male genetic structures Visual Acuity Cell Count Diagnostic Techniques Ophthalmological chemistry.chemical_compound Optics Optical coherence tomography Retinal Diseases Region of interest medicine Humans Prospective Studies Adaptive optics Aged Physics Retina medicine.diagnostic_test business.industry Retinal Middle Aged medicine.disease Ellipsoid eye diseases Ophthalmology medicine.anatomical_structure Cross-Sectional Studies Cone (topology) chemistry Retinal Cone Photoreceptor Cells Maculopathy Female sense organs business Tomography Optical Coherence |
| Zdroj: | American journal of ophthalmology. 160(3) |
| ISSN: | 1879-1891 |
| Popis: | Purpose To investigate the relationship between outer retinal reflectivity on spectral-domain optical coherence tomography and cone density in the corresponding area. Design Prospective cross-sectional observational study. Methods In this institutional-based study, 20 eyes of 10 patients presenting maculopathies with various degrees of impairment of the photoreceptor layer (central serous chorioretinopathy, chronic central serous chorioretinopathy, maculopathy associated with hydroxychloroquine, and healthy eyes) were studied. Selection criteria were intended to ensure good image quality. Inner segment ellipsoid band reflectivity, global retinal reflectivity, and relative inner segment ellipsoid reflectivity (defined as the ratio of inner segment ellipsoid band reflectivity on overall retinal reflectivity) were measured on a longitudinal reflectance profile extracted from the spectral-domain optical coherence tomography B-scan. The cone metrics were measured in the same region of interest, located in the perifoveal area, using an adaptive optics retinal camera. Results Inner segment ellipsoid and relative ellipsoid reflectivity were closely correlated with cone density (Pearson r: 0.72 and 0.70, respectively, P Conclusion Outer retinal reflectivity on the transversal optical coherence tomography scan can be correlated to adaptive optics in terms of photoreceptor density. This quantitative approach using optical coherence tomography images could have important implications in the management of maculopathies. |
| Databáze: | OpenAIRE |
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