Current Prevalence of Oral Helicobacter pylori among Japanese Adults Determined Using a Nested Polymerase Chain Reaction Assay
| Autor: | Tatsuya Ohsumi, Yuichiro Noiri, Shoji Takenaka, Ryoko Nagata |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Molar medicine.medical_specialty Saliva prevalence lcsh:Medicine Oral cavity Gastroenterology Article 03 medical and health sciences 0302 clinical medicine Characteristic distribution stomatognathic system Tongue Internal medicine medicine Immunology and Allergy Medical history Molecular Biology General Immunology and Microbiology biology Helicobacter pylori business.industry lcsh:R biology.organism_classification stomatognathic diseases 030104 developmental biology Infectious Diseases medicine.anatomical_structure characteristic distribution 030211 gastroenterology & hepatology oral cavity business Nested polymerase chain reaction nested polymerase chain reaction (PCR) |
| Zdroj: | Pathogens Volume 10 Issue 1 Pathogens, Vol 10, Iss 10, p 10 (2021) |
| ISSN: | 2076-0817 |
| Popis: | In Japan, gastric Helicobacter pylori infection prevalence has markedly decreased with socioeconomic development. We aimed to investigate the prevalence of oral H. pylori in Japanese adults in 2020 by sex, age, sampling site, and medical history. Unstimulated saliva, supragingival biofilm, and tongue coating were obtained from 88 subjects&ndash with no complaints of upper digestive symptoms&ndash attending a dentist&rsquo s office for dental check-up or disorders. Supragingival biofilm was collected from the upper incisors, lower incisors, upper right molars and lower left molars to analyze the characteristic distribution. Oral H. pylori was detected using nested polymerase chain reaction. Oral H. pylori prevalence did not statistically differ by sex or age. Supragingival biofilm (30.7%) was the most common oral H. pylori niche it was also detected in 4.5% of saliva and 2.3% of tongue samples. The lower incisor was the most common site among the supragingival biofilm samples, followed by the upper incisors, lower left molars, and upper right molars. Oral H. pylori DNA was frequently detected in patients with a history of gastric H. pylori infection. Oral H. pylori has a characteristic distribution independent of sex and age, suggesting that it is part of the normal microflora in the adult oral cavity. |
| Databáze: | OpenAIRE |
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