Rituximab: applications in dermatology
| Autor: | Mitra M Fatourechi, Rokea A el-Azhary, Lawrence E Gibson |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
medicine.medical_specialty
Skin Neoplasms medicine.drug_class Antineoplastic Agents Dermatology Monoclonal antibody Skin Diseases Antibodies Monoclonal Murine-Derived immune system diseases hemic and lymphatic diseases medicine Humans Immunologic Factors biology business.industry Pemphigus vulgaris Antibodies Monoclonal medicine.disease Clinical trial Paraneoplastic pemphigus Graft-versus-host disease Monoclonal Immunology biology.protein Rituximab Antibody business medicine.drug |
| Zdroj: | International journal of dermatology. 45(10) |
| ISSN: | 0011-9059 |
| Popis: | Rituximab is a chimeric anti-CD20 monoclonal antibody which has been used extensively for B-lymphocytic malignancies. In addition, applications for autoimmune diseases have emerged in recent years. Case reports support the use of rituximab in certain dermatologic conditions, including paraneoplastic pemphigus, pemphigus vulgaris, graft versus host disease, and cutaneous B-cell malignancies. Clinical trials are lacking and would be an appropriate next step. |
| Databáze: | OpenAIRE |
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