Association between long-term exposure to Sulfur dioxide pollution and hypertension incidence in northern China: a 12-year cohort study
Autor: | Mengfan Yan, Pengyi Guo, Xuejun Li, Liwen Zhang, Yamin Liu, Xi Chen, Guang-Hui Dong, Naijun Tang, Chaokang Li, Tong Wang, Jie Chen, Zhao Ma, Hui Wu, Anqi Shan, Yu Zhang, Xueli Yang, Baoxin Zhao |
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Rok vydání: | 2020 |
Předmět: |
Adult
Pollution China Health Toxicology and Mutagenesis media_common.quotation_subject Nitrogen Dioxide 010501 environmental sciences complex mixtures 01 natural sciences Cohort Studies chemistry.chemical_compound Air Pollution Environmental health Humans Sulfur Dioxide Environmental Chemistry Medicine Sulfur dioxide Retrospective Studies 0105 earth and related environmental sciences media_common Air Pollutants business.industry Incidence Incidence (epidemiology) Hazard ratio Retrospective cohort study Environmental Exposure General Medicine Middle Aged Confidence interval chemistry Hypertension Cohort Particulate Matter business Cohort study |
Zdroj: | Environmental Science and Pollution Research. 27:21826-21835 |
ISSN: | 1614-7499 0944-1344 |
DOI: | 10.1007/s11356-020-08572-z |
Popis: | Several studies have researched the short-term effect of sulfur dioxide (SO2) exposure on hypertension. However, no evidence has provided the relationship between long-term high pollution exposure of SO2 and morbidity of hypertension in cohort studies in China. This retrospective cohort study aimed to evaluate this association. We used Cox proportional hazards regression models to examine the hazard ratios (HR) for hypertension risks from 1998 to 2009 associated with accumulative exposure of air SO2 among adults in northern China. Annual average concentrations of sulfur dioxide (SO2) were obtained from 15 local environmental monitoring centers. Hypertension was identified according to self-reported diagnostic time and treatment for hypertension with anti-hypertensive medication. Among 37,386 participants, 2619 new cases of hypertension were identified during 426,334 person-years. In the fully adjusted model, HR and 95% confidence interval (CI) of hypertension incidence for each 10 μg/m3 increase in SO2 were 1.176 (1.163 and 1.189). Results from stratified analyses suggested that effects of SO2 on hypertension morbidity were more pronounced in participants |
Databáze: | OpenAIRE |
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