An investigation into the performance of a new mechanical thrombectomy device using bond graph modeling: application to the extraction of blood clots in the middle cerebral artery
| Autor: | Romero Rey, Gregorio, Martínez Muneta, María Luisa, Félez Mindán, Jesús, Pearce, Gillian, Perkinson, N.D. |
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| Rok vydání: | 2012 |
| Předmět: |
Engineering
Thrombus aspiration Medicina 0206 medical engineering 02 engineering and technology 03 medical and health sciences 0302 clinical medicine medicine.artery medicine Extraction (military) Thrombus Simulation Informática business.industry medicine.disease 020601 biomedical engineering Computer Graphics and Computer-Aided Design Mechanical thrombectomy Modeling and Simulation Middle cerebral artery business Bond graph 030217 neurology & neurosurgery Software Biomedical engineering |
| Zdroj: | Simulation: Transactions of the Society for Modelling and Simulation International, ISSN 0037-5497, 2011-08 Archivo Digital UPM Universidad Politécnica de Madrid |
| ISSN: | 1741-3133 0037-5497 |
| DOI: | 10.1177/0037549712463418 |
| Popis: | A number of thrombectomy devices using a variety of methods have now been developed to facilitate clot removal. We present research involving one such experimental device recently developed in the UK, called a ‘GP’ Thrombus Aspiration Device (GPTAD). This device has the potential to bring about the extraction of a thrombus. Although the device is at a relatively early stage of development, the results look encouraging. In this work, we present an analysis and modeling of the GPTAD by means of the bond graph technique; it seems to be a highly effective method of simulating the device under a variety of conditions. Such modeling is useful in optimizing the GPTAD and predicting the result of clot extraction. The aim of this simulation model is to obtain the minimum pressure necessary to extract the clot and to verify that both the pressure and the time required to complete the clot extraction are realistic for use in clinical situations, and are consistent with any experimentally obtained data. We therefore consider aspects of rheology and mechanics in our modeling. |
| Databáze: | OpenAIRE |
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